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. Author manuscript; available in PMC: 2017 Nov 16.
Published in final edited form as: Stem Cells. 2016 Jul 15;34(10):2587–2600. doi: 10.1002/stem.2433

Figure 7.

Figure 7

ADSC and LLP2A-Ale cotreatment increased bone strength. Four-point bending was performed to obtain maximum load and to calculate work-to-failure for all of the treatment groups at day 42 (A). Linear regression was performed for callus structural parameters versus maximum load (B) or work-to-failure (C) and separated for females and the males. *, p < .05 versus PBS-treated group; S, p < .05 versus females. Abbreviations: ADSC, adipose-derived MSC; CV, callus new bone volume; CV/TV, callus volume fraction; LLP2A-Ale, LLP2A-Alendronate; PBS, phosphate buffered saline; PTH, parathyroid hormone; TV, total callus volume; BMD, bone mineral density.