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The lacrimal gland functional unit is comprised of a) the lacrimal gland, b) Sensory afferent nerves from the cornea and conjunctiva, c) motor efferent nerves originating from the central nervous system which innervate lacrimal gland, d) the excretory tear duct for drainage of the excess fluid. Impairment in any components of lacrimal gland function unit can destabilize the tear film and cause the dry eye disease.
