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Link N and fullerol decreased mRNA expression levels of IL-6 and COX-2. Cells were treated with or without IL-1α with addition of LN, fullerol, or LN + fullerol in a pellet culture for 7 days. The cell pellets were harvested for RNA isolation and the gene expression of IL-6 and COX-2 was measured with real-time reverse transcriptionPCR. *p < 0.05 versus control; #p < 0.05 versus IL-1α-treated group.
