Table 2. Aortic and carotid pulsatile hemodynamics before (Pre) and after (Post) administration of sublingual NTG.
| Variable | Pre-NTG | Post-NTG | P value |
|---|---|---|---|
| Central systolic blood pressure, mmHg | 133.6 (27.6) | 120.5 (29.8) | 0.011 |
| Central pulse pressure, mmHg | 59.5 (23.6) | 50 (19.4) | 0.06 |
| Central mean Arterial pressure, mmHg | 96.8 (17) | 90.5 (20.4) | 0.019 |
| Central diastolic blood pressure, mmHg | 74 (15.4) | 70.5 (15.3) | 0.18 |
| Aortic pressure-flow relations | |||
| Aortic Characteristic Impedance, dynes·s/cm5 | 172 (69) | 174 (119) | 0.93 |
| Reflection coefficient, 1st harmonic | 0.093 (26) | 0.002 (26) | 0.017 |
| Reflection coefficient, 2nd harmonic | -0.071 (26) | -0.117 (26) | 0.16 |
| Reflection coefficient, 3rd harmonic | -0.012 (26) | 0.058 (26) | 0.054 |
| Forward wave amplitude, mmHg* | 52.6 (20.2) | 47.6 (16.6) | 0.26 |
| Backward wave amplitude, mmHg* | 19.1 (9.1) | 16.9 (7.5) | 0.21 |
| Backward/Forward wave amplitude* | 0.36 (0.07) | 0.35 (0.08) | 0.33 |
| Time to reflected wave onset, ms | 78 (30) | 89 (44) | 0.22 |
| Buckberg index, % | 130 (33) | 129 (33) | 0.81 |
| Carotid pressure-flow relations | |||
| Carotid Characteristic Impedance, dynes·s/cm5 | 3440 (2757) | 1923 (1277) | 0.002 |
| Carotid Cross-sectional area, cm2 | 0.38 (0.09) | 0.43 (0.1) | <0.0001 |
| Carotid Bed Vascular resistance, dynes·s/cm5 | 19580 (13402) | 13078 (8974) | 0.001 |
*
Computed in the time domain.