Table 3.
Aortic and carotid pulsatile hemodynamics after administration of 12.9 mmol of inorganic nitrate (nitrate-rich beetroot juice, NO3) vs. placebo juice (nitrate-depleted beetroot juice).
Variable | Placebo | NO3 | P value |
---|---|---|---|
Central systolic blood pressure, mmHg | 130 (20.8) | 126.6 (24.2) | 0.50 |
Central pulse pressure, mmHg | 55.3 (16.7) | 51 (18) | 0.34 |
Central diastolic blood pressure, mmHg | 74.7 (12.6) | 75.6 (9.8) | 0.70 |
Central mean Arterial pressure, mmHg | 97.6 (14.8) | 96.4 (15.2) | 0.70 |
Aortic pressure-flow relations | |||
Aortic Characteristic Impedance, dynes·s/cm5 | 163 (74) | 185 (64) | 0.20 |
Reflection coefficient, 1st harmonic | 0.119 (0.15) | -0.001 (0.21) | 0.032 |
Reflection coefficient, 2nd harmonic | -0.03 (0.13) | -0.144 (0.15) | 0.012 |
Reflection coefficient, 3rd harmonic | 0.046 (0.16) | -0.042 (0.16) | 0.091 |
Forward wave amplitude, mmHg* | 47.2 (13.8) | 47.1 (14.1) | 0.98 |
Backward wave amplitude, mmHg* | 16.8 (6) | 18.8 (7.9) | 0.30 |
Backward/Forward wave amplitude* | 0.35 (0.05) | 0.39 (0.08) | 0.08 |
Time to reflected wave onset, ms | 64 (30) | 93 (30) | 0.016 |
Buckberg index, % | 128 (29) | 141 (25) | 0.053 |
Carotid pressure-flow relations | |||
Carotid Characteristic Impedance, dynes·s/cm5 | 3013 (1867) | 2928 (1279) | 0.80 |
Carotid Cross-sectional area, cm2 | 0.37 (0.08) | 0.40 (0.12) | 0.15 |
Carotid Bed Vascular resistance, dynes·s/cm5 | 19391 (13557) | 16624 (6800) | 0.38 |
Computed in the time domain.