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Composition of solid dispersions and hot melt extrusion parameters for each formulation.
| Content of fenofibrate (%) | Polymer carrier
|
Temp. (°C) | Screw speed (rpm) | Torque (%) | |
|---|---|---|---|---|---|
| Content (%) | Grade | ||||
| 20 | 80 | ELF | 120 | 100 | 35–45 |
| 15 | 85 | ELF | 120 | 100 | 35–45 |
| 10 | 90 | ELF | 120 | 100 | 40–50 |
| 10 | 90 | LF | 130 | 100 | 40–50 |
| 10 | 90 | EF | 125 | 100 | 40–50 |
