Fig. 3.

Crystal structures of six mAbs in complex with Pfs25. Crystal structures of a 1190, b 1276, c 1262, d 1269, e 1245, and f 1260 in complex with Pfs25. All crystal structures are shown according to the same Pfs25 orientation. Pfs25 is represented as surface and EGF-like domains 1–4 are colored in wheat, pink, green, and blue, respectively. g Site 1a epitopes for 1190, 1262, 1269, and 1276 antibodies traced onto the surface of Pfs25. h Site 2 epitopes for 1245 and 1260 antibodies traced onto the surface of Pfs25