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. 2017 Nov 16;7:15734. doi: 10.1038/s41598-017-16028-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Real-time detection with field-effect transistor (FET) DNA sensor. A complementary (denoted as c) ssDNA target sequence (red) or non-complementary (denoted as n-c) ssDNA control sequence (blue) was added subsequently yielding three different concentration of 10 nm, 100 nm and 1 µM. Time points of addition are indicated in the figure. A typical response of the FET sensor containing Probe1 and Probe2 to the addition of the complementary and non-complementary targets are shown in (A and B), respectively.