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. 2017 Nov 16;8:1557. doi: 10.1038/s41467-017-01590-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Pediatric MDS cohort. a Pie charts depicting the distribution of the three diagnostic categories and subcategories of the pediatric MDS cohort; Total: n = 77. b Distribution of age (in years) at diagnosis for the pediatric MDS cohort. Lines within boxes represent median age (RCC: 8.4, RAEB: 11.7, AML-MRC: 9.1, MDS/MPN: 2.7) and whiskers represent maximum and minimum. ^***: p < 0.0001 (student’s t-test). AML-MRC AML with myelodysplasia-related changes, RAEB, Refractory anemia with excess blasts; RCC, Refractory cytopenia of childhood