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. 2017 Nov 16;7:15713. doi: 10.1038/s41598-017-15940-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Mutual rescue by the JAK/STAT and insulin signaling pathways. (A–C) Encapsulation rates (A), number of lamellocytes (B) and number of plasmatocytes (C) per larva, when activating insulin signaling and simultaneously suppressing JAK/STAT signaling, or vice versa, with the indicated genetic constructs. Data information: Encapsulation rates were determined in at least three independent experiments, and in total at least 100 larvae were analyzed. For hemocyte counts, at least eight larvae were analyzed for each genotype. Bars show averages and standard deviations. The P-values (unpaired t-test, unequal variance) are indicated, NS: not significant.