Table 1.
Hormone concentrations, ovarian and body weight of rats in the control, PCOS and treated with curcumin groups (n=12). In all groups, control was compared with PCOS group and curcumin treated PCOS was compared with PCOS group
| Groups | Ovarian weight (mg) | Body weight (g) | E2 (ng/ml) | T (ng/ml) | LH (ng/ml) | P4 (ng/ml) | FSH (ng/ml) |
|---|---|---|---|---|---|---|---|
| Control | 12.08±0.5 | 160.3±8.46 | 0.27±0.01 | 0.73±0.03 | 2.36±0.15 | 66.03±7.7 | 1644.76±126.6 |
| PCOS | 20.4±0.15** | 217.6±15*** | 0.63±0.05 *** | 1.41±0.3* | 8.16±1.56*** | 31.12±1.76 ** | 476.82±13.3*** |
| Cucumin100 mg/kg BW | 17.4±0.39*** | 207±16.25*** | 0.36±0.04 | 0.8±0.03 | 4±0.1*** | 35.69±1.07** | 431.13±29.81*** |
| Cucumin200 mg/kg BW | 15.4±0.15 | 196±10.78*** | 0.3±0.01 | 0.8±0.01 | 3.1±0.04*** | 47.36±0.88* | 613.24±13.05*** |
| Cucumin300 mg/kg BW | 14.3±0.2 | 189.20±8.36*** | 0.29±0.01 | 0.77±0.02 | 2.56±0.09 | 50.33±0.41 | 1174.05±15.95** |
| Cucumin400 mg/kg BW | 12.9±0.17 | 184.28±5.9*** | 0.26±0.01 | 0.7±0.01 | 2.39±0.01 | 53.95±0.2 | 1591.21±44.97 |
E2: 17β-estradiol; T: Testosterone; LH: Luteinizing Hormone; P4: Progesterone; FSH: Follicle Stimulating Hormone; PCOS: Polycystic Ovary Syndrome.
***
p<0.001,
**
p<0.01,
*
p<0.05