Table 2.
Morphometry of groups follicular and ovarian follicular diameter (μm) (n=12). In all groups, control was compared with PCOS group and curcumin treated PCOS was compared with PCOS group
| Groups | PMF | PF | PAF | AF | CF | CL | Follicle diameter |
|---|---|---|---|---|---|---|---|
| control | 45±0.1 | 20±0.1*** | 29±0.1*** | 18±0.1*** | 0±0*** | 10±0.1* | 554±0.8*** |
| PCOS | 42±0.05 | 12±0.05 | 17±0.05 | 3±0.15 | 17±0.1 | 4±0.1 | 722±0.3 |
| Cucu100 mg/kg | 48±0.1*** | 14±0.1 | 20±0.15 | 9±0.15** | 11±0.1*** | 18±0.1*** | 667±0.4*** |
| Cucu200 mg/kg | 51±0.05*** | 15±0.11*** | 25±0.1*** | 10±0.11*** | 10±0.1*** | 19±0.1*** | 621±0.3*** |
| Cucu300 mg/kg | 56±0.15*** | 19±0.5*** | 45±0.15*** | 11±0.1*** | 7±0.1*** | 21±0.2*** | 611±0.05*** |
| Cucu400 mg/kg | 66±0.2*** | 21±0.1*** | 46±0.1*** | 14±0.05*** | 1±0.1*** | 25±0.1*** | 598±0.2*** |
In polycystic ovary groups treated with curcumin, a significant increase in the number of follicle and decrease in the ovaries treated with low amount of curcumin was observed in all groups (except group of primordial follicles). In addition, there was a significant decrease in the number of ovarian cysts. PMF: Pri-Mordial Follicles; PF: Primary Follicles: PAF: Pre-Antral Follicles; AF: Antral Follicles; CF: Cystic Follicles; CL: Corpus Luteum.
***
p<0.001,
**
p<0.01,
*
p<0.05