Table 1.

Adjuvant protocols

Adjuvant	Protocol
Antibiotics	Doxycycline 100 mg for 4 days beginning from vaginal egg pick up (VPU) [or] Azithromycin 1g given on the night before VPU [or] Augmentin duo forte BD for 4–5 days post-VPU
Aspirin	100 mg from VPU until pregnancy test
Enoxaparin / Heparin	20–40 mg from VPU until pregnancy test
Steroids	Various protocols 10–30 mg daily Used from stimulation until - Some stopping at pregnancy test - Some stopping until the 1st trimester
Melatonin	4 mg given at night Variable start time, but between 2 days and up to 8 weeks before egg collection Ceased on egg collection
Dopamine agonist	0.5 mg cabergoline orally daily From day of hCG or egg pick up and continuing to 5 days or until pregnancy test [or] Bromocriptine 7.5 mg oral or PV daily starting with hCG trigger until pregnancy test
HCG infusion	Dilution of 1500 IU of hCG in 125 microlitres of blastocyst media, 40 microlitres of this was infused into the uterus 10 min to immediately prior to embryo transfer
DHEA	75 mg daily Given for 3 mths prior to cycle
Testosterone	Given as pre-treatment between 5–21 days before the start of a cycle Given as either a 2.5 mg patch or 10 mg topical gel
Growth hormone	12 IU/day from day of FSH until trigger injection Intramuscular injection
Intralipid infusion	200 mls of Intralipid 20% was given intravenously over two hours 7–10 days before embryo transfer. When a pregnancy was confirmed, additional doses were administered at 7, 9, 11 and 13 weeks
Filgrastim	Intrauterine Given 2 days before embryo transfer 300 μg into uterus 2 days before ET
Co-enzyme Q10	150–300 mg given at night Variable start time, but between 2 days and up to 8 weeks before egg collection Ceased on egg collection