Table 2.
Comparison of demographics and cycle features (median 95%CI)
| Feature | ≥1 Adjuvant (n=1,904) | No adjuvants (n=11,468) | Crude OR | Chi square p |
|---|---|---|---|---|
| Number of previous IVF cycles | 4 (1–16) | 2 (1–11) | <0.001 | |
| BMI | 23.7 (18.2–38.7) | 23.8 (18.3–39.3) | 0.17 | |
| Embryo age (days) | D2-7.1% (136) D3-29.8% (568) D4-3.2% (60) D5/6/7-59.9% (1139) |
D2-5.6% (639) D3-20.5% (2355) D4-2.7% (309) D5/6/7-70.6% (8099) |
<0.001 | |
| Number of 2 embryo transfers | 26.3% (501/1904) | 12.8% (1464/10004) | 2.44 (2.17–2.74) | <0.001 |
| Insemination by ICSI | 83.3% (1586/1904) | 72.1% (8267/11468) | 1.93 (1.70–2.20) | <0.001 |
| Frozen ET | 34.0% (648/1904) | 39.6% (4543/11468) | 0.79 (0.71–0.87) | <0.001 |
| Woman’s age at egg collection (years) | 38.5 (28.1–45.0) | 35.6 (25.9–44.9) | <0.001 | |
| Number of previous pregnancies | 1 (0–5) | 1 (0–4) | 0.016 | |
| Number of previous deliveries | 0 (0–2) | 0 (0–2) | <0.001 | |
| Number of consecutive ETs without chemical pregnancy | 1 (0–9) | 1 (0–6) | <0.001 | |
| Number of consecutive ETs without clinical pregnancy | 1 (0–9) | 1 (0–6) | <0.001 | |
| Number of consecutive ETs without live birth | 2 (0–12) | 1 (0–7) | <0.001 | |
| Site – central | 90.7% (1727/1904) | 62.1% (7121/11468) | 5.96 (5.06–7.01) | <0.001 |
| Site – satellite | 3.9% (74/1904) | 10.9% (1248/11468) | 0.33 (0.26–0.42) | <0.001 |
| Site - interstate | 5.4% (103/1904) | 27.0% (3099/11468) | 0.15 (0.13–0.19) | <0.001 |
| Smoker | 1.9% (37/1904) | 3.0% (344/11468) | 0.64 (0.45–0.91) | 0.01 |
| Year of ET | 2012 (2010–2015) | 2012 (2010–2015) | <0.001 | |
| Diabetic | 1.1% (20/1904) | 0.9% (107/11468) | 1.13 (0.68–1.86) | 0.62 |
| Etiologies | ||||
| Male factor | 0.1% (1/1904) | 0.02% (2/11468) | 3.01 (**–**) | 0.37 |
| Tubal factor | 8.2% (157/1904) | 10.1% (1164/11468) | 0.80 (0.67–0.95) | 0.01 |
| Endometriosis | 11.7% (222/1904) | 11.0% (1264/11468) | 1.07 (0.91–1.24) | 0.41 |
| Fibroids | 3.7% (71/1904) | 2.8% (319/11468) | 1.35 (1.03–1.77) | 0.02 |
| Ovarian dysfunction | 6.2% (118/1904) | 6.9% (787/11468) | 0.90 (0.73–1.10) | 0.28 |
| PCOS | 3.0% (58/1904) | 6.1% (703/11468) | 0.48 (0.36–0.64) | <0.001 |
| Idiopathic | 23.2% (442/1904) | 26.8% (3075/11468) | 0.83 (0.74–0.93) | <0.001 |
| Unknown | 31.0% (590/1904) | 26.8% (3071/11468) | 1.23 (1.10–1.37) | <0.001 |
| Ultrasound - endometrioma | 0.3% (5/1904) | 0.4% (44/11468) | 0.68 (0.24–1.80) | 0.42 |
| Ultrasound - PCO | 15.7% (298/1904) | 18.8% (2160/11468) | 0.80 (0.70–0.91) | <0.001 |
**
Confidence limits invalid