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. 2017 Jul 19;5(4):503–514. doi: 10.1002/iid3.186

Figure 3.

Figure 3

Effect of Mincle on surface marker expression by GM‐CSF and M‐CSF/IL‐4 BMMs. (A) Cell surface expression of Mincle in GM‐CSF and M‐CSF/IL‐4 differentiated BMMs from C57BL/6 bone marrow treated with 40 or 100 µg/mL TDB, or 100 ng/mL LPS as positive control, for 6, 24, and 48 h. Cell surface expression of (B) CD115 and percentage of CD115high cells, (C) CD11b, (D) CD206 in GM‐CSF and M‐CSF/IL‐4 differentiated BMMs from Mincle−/− bone marrow treated with 40 or 100 µg/mL TDB, or 100 ng/mL LPS as positive control, for 24 h. Mean ± SEM of triplicate samples from at least three independent experiments are shown. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.005; ****P ≤ 0.001 (two tailed Student's t‐test, 2‐way ANOVA with Bonferroni post hoc test).