Figure 6.

AC clinical signs are decreased by administration of topical CCR7 Ab blockade. Actively immunized mice were challenged once daily for 4 days with OVA eye drops containing 1% anti-CCR7 Ab or isotype control Ab. A: Mice were scored for clinical signs biomicroscopically at 20 minutes, 6 hours, and 24 hours post challenge. B: Representative clinical images on challenge days 3 and 4 are presented. Data are derived from n = 5 hosts per group; figure represents multiple independent experiments. (*P < 0.05).