Fig. 2.

Hierarchical clustering of variable probes in mouse (A) and in rat (B). Four clusters were defined for experiments and seven for probes as reflected by the dendrogram colours. Below the heatmaps, localisation of experiments from each series are shown in black, one line per series. FC: fold change. C and D. Metadata term frequencies of the two biggest experiment clusters were compared for mouse (C) and rat (D). Colour-code matches the experiments trees in panels A and B. E. Homology relationships between probe clusters between rat (X-axis) and mouse (Y-axis). Cell colour: Jaccard index. Cell label: Bonferroni adjusted P-values: ***≤ 0.0001, **≤ 0.001, *≤ 0.01, +≤ 0.05. Cluster number colours match the probes dendrogram colours in panels A and B. The numbers in parenthesis denote the number of probes in each cluster. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)