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. 2017 Sep 28;9(10):277. doi: 10.3390/v9100277

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Effects of AMP removal on p24 maturation in HIV-1 BaL chronically-infected MDM. p24 maturation was expressed as the ratio of p24 amount on p55 amount in cell lysates. p24 and p55 amounts were determined by ELISA; (B) western blot analysis showing p24 and p55 amount detected in cell lysates from chronically-infected macrophages. * Indicates the removal of AMP. In (A,B), the following experimental conditions were tested: Group 1, 18th day infection and 7th day treatment; Group 2, 18.5th day infection and 7.5th day treatment; Group 3, 19th day infection and 8th day treatment. HIV-1 BaL refers to an HIV-1 strain isolated from alveolar macrophages by a bronchoalveolar lavage.