Table 1.
Demographic data and dementia diagnostic parameters.
| AD (n = 22) | Non-AD (n = 16) | Other Neurological Disorders (n = 20) | |
|---|---|---|---|
| Age (years) | 69 ± 9 | 63 ± 8 | 65 ± 17 |
| Male sex, n (%) | 12 (54) | 9 (56) | 10 (50) |
| Aβ 1–42 (ng/L) | 416 (177–674) | 675 *** (288–1540) | N.E. |
| Tau (ng/L) | 449 (109–1644) | 204 *** (22–564) | N.E. |
| Phospo-Tau (ng/L) | 80 (25–742) | 33 *** (3–64) | N.E. |
| TMAO (µmol/L) | 0.520 (0.32–1.15) | 0.710, (0.56–1.50) | 0.570, (0.42–1.00) |
Data are expressed as mean ± S.D. for normally distributed values or as median (interquartile range) for data that are not normally distributed. The one way ANOVA test was applied to compare the three groups for age; the non-parametric two-tailed Mann Whitney test was applied to compare AD and non-AD subjects for CSF neurobiomarkers. *** p < 0.01 vs. AD. AD: Alzheimer’s disease; non-AD: non-AD related dementia. N.E.: not evaluated.