Table 2.
Morphometric parameters and blood biomarkers of the experimental groups (mean ± SD, n = 10).
| Diet */Time (Day of Sampling) | ||||||
|---|---|---|---|---|---|---|
| RMD | HFD | HFD + C | ||||
| Morphometric parameters | 0 | 60 | 0 | 60 | 0 | 60 |
| Weight (g) | 352.70 ± 29.32 b | 453.45 ± 28.00 a | 350.25 ± 30.66 b | 493.00 ± 42.90 a | 351.33 ± 26.82 b | 487.33 ± 30.96 a |
| BMI | 0.61 ± 0.03 a | 0.62 ± 0.02 a | 0.62 ± 0.04 a | 0.67 ± 0.04 a | 0.76 ± 0.06 a | 0.75 ± 0.02 a |
| Blood biomarkers | ||||||
| GLU (mg/dL) | 85.01 ± 8.12 a | 85.75 ± 6.71 a | 84.53 ± 9.26 b | 151.73 ± 8.85 a | 86.81 ± 13.65 b | 148.96 ± 16.45 a |
| TAG (mg/dL) | 86.00 ± 12.00 a | 81.20 ± 13.30 a | 91.10 ± 15.30 a | 102.8 ± 25.09 a | 87.30 ± 19.90 a | 94.08 ± 18.93 a |
| TC (mg/dL) | 61.10 ± 13.52 a | 59.15 ± 10.21 a | 58.04 ± 13.53 a | 56.18 ± 10.21 a | 57.26 ± 14.12 a | 54.44 ± 3.57 a |
| TBS (µmol/L) | 5.98 ± 1.74 a | 6.59 ± 1.35 a | 5.85 ± 1.74 a | 1.96 ± 0.41 b | 5.80 ± 1.97 a | 2.53 ± 0.81 b |
| HDL (mg/dL) | 44.19 ± 5.83 a | 39.70 ± 6.53 a | 43.37 ± 6.30 a | 37.24 ± 4.66 a | 39.70 ± 6.53 a | 35.33 ± 9.27 a |
| LDL (mg/dL) | 13.04 ± 3.34 a | 17.00 ± 4.03 a | 13.48 ± 2.94 b | 19.51 ± 1.97 a | 14.21 ± 3.31 a | 17.66 ± 2.01 a |
* Diet: RMD = Rodent Maintenance Diet; HFD = High Fat Diet; HFD + C = High Fat Diet + Citrolive™; Morphometric parameters: BMI = body mass index Blood biomarkers: GLU = glucose; HDL = high density lipoprotein cholesterol; LDL = low density lipoprotein cholesterol; AST = aspartate transaminase; ALT = alanine transaminase; TAG = triacylglycerol; TC = total cholesterol; TBS = total bile salts; a,b Values not shearing the same superscript within the same diet and parameter or biomarker are significantly different for p < 0.05.