Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pathogenesis of NAFLD. Based on the “multiple hit” model, dietary habits, insulin resistance, visceral adiposity, inflammatory state, oxidative stress, alteration in microbiome, and genetic predisposition, are all recognized risk factors for NAFLD. DNL: de novo lipogenesis; FFA: free fatty acids; IL-6: interleukin-6; IL-1β: interleukin-1β; LPS: lipopolysaccharide; NAFLD: non-alcoholic fatty liver disease; NASH: non-alcoholic steatohepatitis; TNF-α: tumor necrosis factor-α.
