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. 2017 Oct 23;9(10):1152. doi: 10.3390/nu9101152

Figure 4.

Figure 4

Uptake of vitamin D forms by Caco-2 cells in the presence of membrane protein inhibitors. Form (a) Uptake of D3, 1α(OH)D3, and 25(OH)D3 in the presence or absence of BLT1 (10 µM), an inhibitor of SR-BI (n = 3); (b) Uptake of D3, 1α(OH)D3, and 25(OH)D3 in the presence or absence of ezetimibe glucuronide (10 µM), an inhibitor of NPC1L1 (n = 3); (c) Uptake of D3, 1α(OH)D3, and 25(OH)D3 in the presence or absence of simvastatin (100 µM), an inhibitor of ASBT (n = 3). ** p < 0.01; *** p < 0.001, NS: not significant.