| The total annual number of US Medicaid-reimbursed prescriptions for quinolones (branded and generic) increased 402%. |
| More than 80% of quinolone prescriptions reimbursed by Medicaid were for ciprofloxacin and levofloxacin. |
| From 1991 to 2015, Medicaid spending on quinolone medications rose by 245.5%, from US$11.8 million to US$40.8 million. |
| The average payment per prescription for quinolones increased from US$43.8 in the first quarter of 1991 to US$87.6 in the second quarter of 2015. |