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. 2017 Nov 10;10:2649–2655. doi: 10.2147/JPR.S142896

Table 2.

Patient-controlled intravenous analgesia

Parameters Time points Group S Group OS1 Group OS2 Group O P1 P2 P3 P4 P5 P6 P0
The number of PCIA boluses 6 h 5.4 (4.2)* 5.0 (3.7)* 3.2 (1.4) 1.6 (0.5) 0.043 0.000 0.000 0.020 0.569 0.004 0.000
12 h 10.9 (8.8)* 9.0 (5.5)* 5.7 (2.6) 2.9 (0.8) 0.049 0.000 0.000 0.024 0.162 0.000 0.000
24 h 17.2 (14.0)* 15.4 (10.0)* 10.5 (5.5) 4.8 (1.2) 0.021 0.000 0.000 0.045 0.432 0.006 0.000
The amount of opioid consumption 6 h 15.8 (6.3)* 14.7 (5.8)* 11.8 (2.5) 8.7 (1.3) 0.010 0.000 0.000 0.002 0.363 0.001 0.000
12 h 32.0 (2.5)* 28.5 (11.8)* 23.5 (6.6) 17.7 (2.2) 0.021 0.000 0.000 0.041 0.153 0.001 0.000
24 h 52.4 (18.4)* 48.2 (16.8)* 40.9 (9.7) 33.0 (2.6) 0.029 0.000 0.000 0.043 0.233 0.002 0.000

Notes: Group S (sufentanil 100 μg), group OS1 (sufentanil 70 μg, oxycodone 30 mg), group OS2 (sufentanil 50 μg, oxycodone 50 mg), and group O (oxycodone 100 mg). Ramosetron 0.3 mg was added to each group. In all groups, the drugs were diluted to 100 mL. Values are expressed as mean ± SD.

*

P<0.05. P1, group O vs group OS2; P2, group O vs group OS1; P3, group O vs group S; P4, group OS1 vs group OS2; P5, group S vs group OS1; P6, group S vs group OS2; P0, comparing groups.

Abbreviation: PCIA, patient-controlled intravenous analgesia.