Table 1.
Trends by age group.
| Total | 18–37 years | 38–57 years | 58–77 years | 78–97 years | p-value | |
|---|---|---|---|---|---|---|
| Total cases | 343 | 37 | 138 | 137 | 31 | |
| 30-day mortality | 71 (20.7%) | 8 (21.6%) | 22 (15.9%) | 38 (27.7%) | 3 (9.7%) | 0.039 |
| 90-day mortality | 90 (26.2%) | 8 (21.6%) | 29 (21.0%) | 49 (35.8%) | 4 (12.9%) | 0.009 |
| 180-day mortality | 100 (29.2%) | 10 (27.0%) | 32 (23.2%) | 53 (38.2%) | 5 (16.1%) | 0.012 |
| Valve surgery | 87 (25.4%) | 8 (21.6%) | 54 (39.1%) | 24 (18.1%) | 1 (3.2%) | <0.001 |
| Embolic phenomena | 104 (29.5%) | 11 (29.7%) | 51 (37.0%) | 36 (26.3%) | 6 (19.4%) | 0.127 |
| Brain | 56 (16.3%) | 5 (13.5%) | 32 (23.2%) | 15 (10.9%) | 4 (12.9%) | 0.043 |
| Pulmonary | 22 (6.4%) | 4 (10.8%) | 9 (6.5%) | 7 (5.1%) | 2 (6.3%) | – |
| Abdominal organs | 20 (5.8%) | – | 12 (8.7%) | 8 (5.8%) | – | – |
| Other location | 30 (8.7%) | 3 (8.1%) | 10 (7.2%) | 17 (12.4%) | – | – |
| 30-day mortality | 19 (18.3%) | 2 (18.2%) | 6 (11.8%) | 10 (27.8%) | 1 (16.7%) | – |
| Causative organism | ||||||
| S. aureus | 125 (36.4%) | 19 (51.4%) | 53 (38.4%) | 45 (32.8%) | 8 (25.8%) | 0.109 |
| MRSA | 60 (17.5%) | 5 (13.5%) | 30 (21.7%) | 22 (16.1%) | 3 (9.7%) | 0.303 |
| CoNS | 48 (14.0%) | 4 (10.8%) | 14 (10.1%) | 24 (17.5%) | 6 (19.4%) | 0.244 |
| MR | 23 (6.7%) | 1 (2.7%) | 7 (5.1%) | 13 (9.5%) | 2 (6.3%) | – |
| Enterococcus | 42 (12.2%) | 2 (5.4%) | 13 (9.4%) | 19 (13.9%) | 8 (25.8%) | 0.041 |
| VGS | 54 (15.7%) | 3 (8.1%) | 25 (18.1%) | 23 (16.7%) | 3 (9.7%) | – |
| Other strep | 31 (9.0%) | 3 (8.1%) | 17 (12.3%) | 9 (6.6%) | 2 (6.3%) | – |
| Other bacteria | 26 (7.6%) | 3 (8.1%) | 11 (8.0%) | 9 (6.6%) | 3 (9.7%) | – |
| Serology positive | 4 (1.2%) | 1 (2.7%) | – | 3 (2.2%) | – | – |
| Fungal | 7 (2.0%) | 3 (8.1%) | 2 (1.5%) | 2 (1.5%) | – | – |
| Valve type affected | ||||||
| Native | 256 (74.6%) | 27 (73.0%) | 106 (76.8%) | 95 (69.3%) | 22 (71.0%) | 0.572 |
| Prosthetic | 63 (18.4%) | 6 (16.2%) | 22 (15.9%) | 30 (21.9%) | 2 (6.5%) | 0.193 |
| Device | 27 (7.9%) | 3 (8.1%) | 7 (5.1%) | 7 (5.1%) | 7 (22.6%) | 0.004 |
MRSA: methicillin-resistant Staphylococcus aureus; CoNS: coagulase-negative Staphylococci; MR: methicillin resistant; VGS: viridans group streptococci.
Percent of total are in parentheses with exception of embolic 30-day mortality which is a percent of embolic phenomena for that age group. Emboli are classified by location.