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. 2017 Nov 17;13:1744806917743479. doi: 10.1177/1744806917743479

Figure 1.

Figure 1.

Synthesis of PolyMorphine (5). PolyMorphine 5 was synthesized from the reaction of morphine 1 and glutaric anhydride 2 via ring opening followed by the acetylation of the diacid 3 and polymerization of the monomer 4 by melt condensation.