Table 2.
Protocol and Genotype | n | Days to Reentrain | p value |
---|---|---|---|
Advancing LD | |||
Zfhx3Flox/Flox;UBC-Cre+ | 6 | 3.0 ± 0.5 | n/a |
Zfhx3Flox/+;UBC-Cre+ | 10 | 5.6 ± 0.5 | 0.0471 |
Zfhx3Flox/Flox;UBC-Cre− | 9 | 4.9 ± 0.7 | 0.097 |
Zfhx3Flox/+;UBC-Cre− | 10 | 6.6 ± 0.5 | 0.0109 |
Zfhx3+/+;UBC-Cre+ | 10 | 6.3 ± 0.7 | 0.0146 |
Delaying LD | |||
Zfhx3Flox/Flox;UBC-Cre+ | 5 | 3.0 ± 0.8 | n/a |
Zfhx3Flox/+;UBC-Cre+ | 6 | 2.8 ± 0.2 | 1.0000 |
Zfhx3Flox/Flox;UBC-Cre− | 4 | 3.8 ± 0.6 | 1.0000 |
Zfhx3Flox/+;UBC-Cre− | 8 | 3.1 ± 0.3 | 1.0000 |
Zfhx3+/+;UBC-Cre+ | 4 | 3.3 ± 0.5 | 1.0000 |
The table provides the number of days (mean ± standard error of the mean) taken to reentrain to a 6-h advance and a 6-h delay in the light-dark cycle for all genotypes tested in the jet lag protocol. All data shown are for animals after tamoxifen treatment. P values shown are for that genotype compared with Zfhx3Flox/Flox;UBC-Cre+ and Bonferroni corrected for multiple comparison.