Fig. 1.

Systematic screening of antibodies to P. falciparum antigens for cross-strain activity. The 3D7 (black bars) and Dd2 (gray bars) strains of P. falciparum were grown for 48 h in in vitro culture in the presence of purified rabbit polyclonal IgG raised against members of a panel of recombinant merozoite protein ectodomains. Bars represent mean growth relative to positive control wells lacking antibodies, and error bars represent SD (n = 3). Merozoite ectodomains are grouped by their known or predicted subcellular location.