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. 2017 Oct 23;114(45):12045–12050. doi: 10.1073/pnas.1702944114

Table S3.

Output of Cox regression model for all antigen combinations

Antigen combination Sample size Events Hazard ratio Lower 95% CI Upper 95% CI Cox model P value Cox BH-adjusted P value ZPH P value Global ZPH P value
PfEBA181 + PfRH5 277 191 0.3240 0.1752 0.5991 0.0003 0.0206 0.7851 0.3084
PfEBA181 + PfRAMA + PfRH5 277 191 0.2167 0.0756 0.6209 0.0044 0.2691 0.7497 0.2551
PfEBA181 + PfMSRP5 + PfRAMA + PfRH5 277 191 0.2167 0.0756 0.6209 0.0044 0.2691 0.7497 0.2551
PfEBA181 + PfSERA9 + PfRH5 277 191 0.3735 0.1858 0.7508 0.0057 0.3421 0.9285 0.3081
PfEBA181 + PfMSRP5 + PfRH5 277 191 0.3262 0.1450 0.7339 0.0068 0.3998 0.6043 0.2589
PfMSRP5 + PfRAMA + PfRH5 277 191 0.2761 0.1063 0.7169 0.0082 0.4756 0.7238 0.2737
PfRAMA + PfRH5 276 191 0.2795 0.1077 0.7253 0.0088 0.5013 0.7189 0.2821
PfEBA181 + PfMSRP5 + PfRAMA 277 191 0.4329 0.2310 0.8115 0.0090 0.5045 0.9215 0.2569
PfMSRP5 + PfRH5 276 191 0.4064 0.2049 0.8062 0.0100 0.5494 0.5335 0.2268
PfMSRP5 + PfRAMA 277 191 0.4904 0.2742 0.8773 0.0163 0.8828 0.9782 0.2833
PfRH5 273 189 0.5862 0.3763 0.9134 0.0183 0.9684 0.3697 0.2768
PfRAMA + PfSERA9 + PfRH5 277 191 0.3265 0.1152 0.9259 0.0353 0.9996 0.6314 0.2652
PfEBA181 + PfRAMA + PfSERA9 + PfRH5 277 191 0.3265 0.1152 0.9259 0.0353 0.9996 0.6314 0.2652
PfMSRP5 + PfRAMA + PfSERA9 + PfRH5 277 191 0.3265 0.1152 0.9259 0.0353 0.9996 0.6314 0.2652
PfEBA181 + PfMSRP5 + PfRAMA + PfSERA9 + PfRH5 277 191 0.3265 0.1152 0.9259 0.0353 0.9996 0.6314 0.2652
PfSERA9 + PfRH5 276 191 0.5580 0.3146 0.9897 0.0460 0.9996 0.9942 0.2751
PfEBA181 + PfMSRP5 + PfSERA9 + PfRH5 277 191 0.3973 0.1551 1.0176 0.0544 0.9996 0.6009 0.2643
PfMSRP5 + PfSERA9 + PfRH5 276 191 0.4694 0.1974 1.1164 0.0871 0.9996 0.6514 0.2498
PfMSRP5 + PfRAMA + PfSERA9 277 191 0.6097 0.3164 1.1749 0.1393 0.9996 0.4759 0.2533
PfEBA181 + PfRAMA 277 191 0.6867 0.4154 1.1351 0.1427 0.9996 0.3132 0.2147
PfRAMA 277 191 0.7079 0.4426 1.1322 0.1494 0.9996 0.3232 0.2293
PfMSRP5 277 191 0.7740 0.5293 1.1320 0.1866 0.9996 0.8994 0.3040
PfEBA181 + PfMSRP51 277 191 0.7786 0.5086 1.1920 0.2494 0.9996 0.7291 0.2966
PfEBA181 + PfMSRP5 + PfRAMA + PfSERA9 277 191 0.6844 0.3534 1.3254 0.2608 0.9996 0.5326 0.2656
PfSERA9 277 191 1.1622 0.8602 1.5702 0.3275 0.9996 0.0328 0.0630
PfCyRPA + PfSERA9 277 191 0.6607 0.2095 2.0840 0.4795 0.9996 0.2012 0.1962
PfEBA181 + PfSERA9 277 191 1.1157 0.8100 1.5369 0.5027 0.9996 0.0599 0.0929
PfCyRPA 277 191 0.7925 0.3481 1.8047 0.5797 0.9996 0.4000 0.2617
PfCyRPA + PfMSRP5 + PfSERA9 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfMSRP5 + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfRAMA + PfSERA9 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfRAMA + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfEBA181 + PfMSRP5 + PfSERA9 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfEBA181 + PfMSRP5 + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfEBA181 + PfRAMA + PfSERA9 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfEBA181 + PfRAMA + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfMSRP5 + PfRAMA + PfSERA9 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfMSRP5 + PfRAMA + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfMSRP5 + PfSERA9 + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfRAMA + PfSERA9 + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfEBA181 + PfMSRP5 + PfRAMA + PfSERA9 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfEBA181 + PfMSRP5 + PfRAMA + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfEBA181 + PfMSRP5 + PfSERA9 + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfEBA181 + PfRAMA + PfSERA9 + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfMSRP5 + PfRAMA + PfSERA9 + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfEBA181 + PfMSRP5 + PfRAMA + PfSERA9 + PfRH5 277 191 0.5872 0.0806 4.2792 0.5993 0.9996 0.3609 0.2443
PfCyRPA + PfMSRP5 277 191 0.7493 0.1832 3.0655 0.6881 0.9996 0.1311 0.1491
PfCyRPA + PfRAMA 277 191 0.7493 0.1832 3.0655 0.6881 0.9996 0.1311 0.1491
PfCyRPA + PfEBA181 + PfMSRP5 277 191 0.7493 0.1832 3.0655 0.6881 0.9996 0.1311 0.1491
PfCyRPA + PfEBA181 + PfRAMA 277 191 0.7493 0.1832 3.0655 0.6881 0.9996 0.1311 0.1491
PfCyRPA + PfMSRP5 + PfRAMA 277 191 0.7493 0.1832 3.0655 0.6881 0.9996 0.1311 0.1491
PfCyRPA + PfEBA181 + PfMSRP5 + PfRAMA 277 191 0.7493 0.1832 3.0655 0.6881 0.9996 0.1311 0.1491
PfRAMA + PfSERA9 277 191 0.9129 0.5488 1.5185 0.7256 0.9996 0.7739 0.3102
PfCyRPA + PfRH5 277 191 0.8149 0.1980 3.3536 0.7768 0.9996 0.1562 0.1642
PfCyRPA + PfEBA181 + PfSERA9 277 191 0.8149 0.1980 3.3536 0.7768 0.9996 0.1562 0.1642
PfCyRPA + PfEBA181 + PfRH5 277 191 0.8149 0.1980 3.3536 0.7768 0.9996 0.1562 0.1642
PfCyRPA + PfSERA9 + PfRH5 277 191 0.8149 0.1980 3.3536 0.7768 0.9996 0.1562 0.1642
PfCyRPA + PfEBA181 + PfSERA9 + PfRH5 277 191 0.8149 0.1980 3.3536 0.7768 0.9996 0.1562 0.1642
PfCyRPA + PfEBA181 277 191 0.8770 0.2758 2.7890 0.8240 0.9996 0.0594 0.0941
PfMSRP5 + PfSERA9 277 191 1.0498 0.6789 1.6231 0.8271 0.9996 0.7816 0.3178
PfEBA181 + PfMSRP5 + PfSERA9 277 191 1.0508 0.6597 1.6738 0.8348 0.9996 0.7149 0.3110
PfEBA181 277 191 1.0325 0.7435 1.4340 0.8485 0.9996 0.0032 0.0125
PfEBA181 + PfRAMA + PfSERA9 277 191 0.9999 0.6005 1.6647 0.9996 0.9996 0.6747 0.3042

Details of the analyses are described in SI Methods. BH, Benjamini–Hochberg; CI, confidence interval; ZPH, assumption testing using the cox.zph function from the survival package in R.