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. 2017 Oct 23;114(45):E9445–E9454. doi: 10.1073/pnas.1711924114

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Fig. 4. — Control patient (C1). (A) Pretreatment radiograph of tooth 13 with existing apical lesion (white arrow). (B) Completed backfill (white arrow) and apical seal with unmodified GP. (C) Six-month follow-up radiograph shows the apical lesion with increased bone density (white arrow). (D) Lesion diameter at pretreatment (red) and 6-mo follow-up (blue) appointments. (E) A 5.07-mm apical lesion diameter was visible on the pretreatment radiograph. (F) A 4.19-mm apical lesion diameter was visible on the 6-mo follow-up radiograph.