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. 2017 Nov 15;23:785–798.

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Copyright © 2017 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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Efficacy of brimonidine alone or combined with pirenzepine on inhibiting the thinning of the sclera. The hematoxylin and eosin (H&E) stains, the Van Gieson (VG) stains, and the thickness of the sclera of each group are shown. A: H&E stains of each group. B: VG stains of each group. C: Thickness of the sclera in each group according to the H&E stains. D: Thickness of the sclera in each group according to the VG stain. *p<0.05 (n=6). (A = Group A 2% pirenzepine group; B = Group B 0.2% brimonidine group; C = Group C 0.1% brimonidine group; D = Group D 2% pirenzepine + 0.2% brimonidine group; E = Group E 2% pirenzepine + 0.1% brimonidine group; F = Group F medium group; L: left; R: right).