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. 2017 Nov 6;19(Suppl 5):v1–v88. doi: 10.1093/neuonc/nox158

Table 17.

Estimated Number of Casesa,b of Brain and Other Central Nervous System Tumors Overall and by Behavior by Major Histology Grouping and Histology, 2017, 2018

Histology 2017 Estimated New Cases 2018 Estimated New Cases
All Malignant Non-Malignant All Malignant Non-Malignant
Tumors of Neuroepithelial Tissue c 23,000 21,340 1,660 23,280 21,590 1,680
Pilocytic astrocytoma 1,100 1,100 -- 1,120 1,120 --
Diffuse astrocytoma 1,410 1,410 -- 1,400 1,400 --
Anaplastic astrocytoma 1,570 1,570 -- 1,630 1,630 --
Unique astrocytoma variants 260 180 80 270 190 80
Glioblastoma 12,500 12,500 -- 12,760 12,760 --
Oligodendroglioma 670 670 -- 660 650 --
Anaplastic oligodendroglioma 380 380 -- 390 390 --
Oligoastrocytic tumors 460 460 -- 440 430 --
Ependymal tumors 1,340 710 630 1,340 690 640
Glioma malignant, NOS 1,400 1,400 -- 1,380 1,380 --
Choroid plexus tumors 150 -- 120 150 -- 120
Other neuroepithelial tumors -- -- -- -- -- --
Neuronal and mixed neuronal-glial tumors 930 210 710 930 220 710
Tumors of the pineal region 180 90 80 180 100 80
Embryonal tumors 630 600 -- 610 590 --
Tumors of Cranial and Spinal Nerves c 7,230 -- 7,190 7,400 -- 7,360
Nerve sheath tumors 7,220 -- 7,180 7,390 -- 7,350
Other tumors of cranial and spinal nerves -- -- -- -- -- --
Tumors of Meninges c 30,040 470 29,560 30,270 470 29,800
Meningioma 29,100 310 28,800 29,320 300 29,020
Mesenchymal tumors 300 90 210 310 90 210
Primary melanocytic lesions -- -- -- -- -- --
Other neoplasms related to the meninges 600 50 550 600 50 550
Lymphomas and Hematopoietic Neoplasms c 1,690 1,690 -- 1,720 1,720 --
Lymphoma 1,630 1,620 -- 1,650 1,650 --
Other hematopoietic neoplasms 60 60 -- 70 70 --
Germ Cell Tumors and Cysts c 310 210 100 310 210 100
Germ cell tumors, cysts and heterotopias 310 210 100 310 210 100
Tumors of Sellar Region c 13,680 60 13,620 13,840 60 13,770
Tumors of the pituitary 13,060 50 13,000 13,210 60 13,150
Craniopharyngioma 620 -- 620 620 -- 620
Unclassified Tumors c 4,110 1,440 2,660 4,090 1,460 2,630
Hemangioma 990 -- 980 940 -- 930
Neoplasm, unspecified 3,100 1,430 1,670 3,130 1,450 1,680
All other -- -- -- -- -- --
TOTAL d 78,370 23,570 54,800 79,870 24,720 55,150

aSource: Estimation based on CBTRUS NPCR and SEER 2000-2014 data for malignant tumors, and NPCR and SEER 2006-2014 data for non- malignant tumors.

bRounded to the nearest 10. Numbers may not add up due to rounding.

cMajor histology grouping estimates are calculated by summing estimates for all included histologies.

dTotal estimate is based on overall estimate, histology-specific estimates may not add up to total.

Estimated number is less than 50. These cases are included in overall rates.

Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results program; CI, confidence interval; NOS, not otherwise specified.