Table 21.
One-, Two-, Three-, Four-, Five-, and Ten-Year Relative Survival Ratesa,b for Selected Malignant Brain and Other Central Nervous System Tumors by Histology, SEER 18 Registries, 2000-2014c
| Histology | N d | 1-Year | 2-Year | 3-Year | 4-Year | 5-Year | 10-Year | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | ||
| Pilocytic astrocytoma | 3,896 | 97.9 | 97.3-98.3 | 96.5 | 95.8-97.0 | 95.4 | 94.6-96.1 | 94.6 | 93.8-95.4 | 94.1 | 93.2-94.9 | 92.2 | 91.0-93.3 |
| Diffuse astrocytoma | 6,144 | 74.7 | 73.5-75.8 | 63.9 | 62.7-65.2 | 57.6 | 56.3-58.9 | 53.3 | 51.9-54.6 | 50.1 | 48.7-51.5 | 39.3 | 37.8-40.9 |
| Anaplastic astrocytoma | 4,177 | 64.9 | 63.3-66.3 | 46.3 | 44.6-47.9 | 37.7 | 36.0-39.3 | 32.9 | 31.3-34.5 | 29.8 | 28.2-31.4 | 20.8 | 19.1-22.5 |
| Glioblastoma | 33,951 | 39.7 | 39.2-40.3 | 17.2 | 16.7-17.6 | 10.1 | 9.7-10.4 | 7.1 | 6.8-7.4 | 5.5 | 5.2-5.8 | 2.9 | 2.6-3.1 |
| Oligodendroglioma | 3,262 | 94.5 | 93.6-95.3 | 90.4 | 89.2-91.4 | 87.1 | 85.8-88.3 | 84.1 | 82.7-85.5 | 81.3 | 79.7-82.8 | 65.7 | 63.4-67.9 |
| Anaplastic oligodendroglioma | 1,397 | 83.9 | 81.7-85.8 | 71.5 | 68.9-73.9 | 64.9 | 62.1-67.6 | 60.3 | 57.4-63.1 | 56.6 | 53.6-59.5 | 42.6 | 39.1-46.0 |
| Ependymal tumors | 2,927 | 94.3 | 93.4-95.2 | 90.5 | 89.2-91.6 | 87.8 | 86.4-89.1 | 85.9 | 84.4-87.3 | 84.5 | 82.8-86.0 | 79.5 | 77.3-81.5 |
| Oligoastrocytic tumors | 2,154 | 88.8 | 87.3-90.1 | 79.0 | 77.1-80.8 | 73.1 | 71.0-75.1 | 67.8 | 65.6-69.9 | 63.7 | 61.3-65.9 | 49.0 | 46.1-51.9 |
| Glioma malignant, NOS | 4,806 | 65.9 | 64.4-67.2 | 55.7 | 54.2-57.2 | 52.5 | 51.0-54.0 | 50.8 | 49.3-52.4 | 49.6 | 48.0-51.1 | 44.6 | 42.8-46.3 |
| Neuronal and mixed neuronal-glial tumors | 567 | 91.5 | 88.6-93.6 | 85.4 | 81.8-88.3 | 80.7 | 76.6-84.1 | 78.2 | 73.9-81.9 | 77.7 | 73.2-81.6 | 64.3 | 57.7-70.0 |
| Embryonal tumors | 2,943 | 81.5 | 80.1-82.9 | 71.8 | 70.1-73.5 | 67.1 | 65.2-68.8 | 64.6 | 62.7-66.4 | 61.8 | 59.9-63.7 | 54.9 | 52.7-57.0 |
| Medulloblastomae | 1,775 | 89.1 | 87.5-90.5 | 82.7 | 80.8-84.4 | 78.3 | 76.2-80.3 | 75.8 | 73.6-77.9 | 73.0 | 70.6-75.2 | 64.7 | 61.8-67.4 |
| Primitive neuroectodermal tumorf | 612 | 74.8 | 71.1-78.1 | 58.3 | 54.1-62.2 | 52.0 | 47.8-56.1 | 48.8 | 44.5-52.9 | 46.9 | 42.6-51.0 | 40.9 | 36.5-45.3 |
| Atypical teratoid/ rhabdoid tumorg | 263 | 51.4 | 45.1-57.3 | 37.4 | 31.2-43.5 | 33.7 | 27.7-39.8 | 33.1 | 27.1-39.3 | 31.7 | 25.6-37.9 | 28.6 | 22.3-35.3 |
| Other embryonal histologiesh | 293 | 77.5 | 72.1-82.0 | 66.2 | 60.1-71.5 | 61.5 | 55.3-67.1 | 59.2 | 52.8-64.9 | 53.8 | 47.2-59.9 | 50.2 | 43.3-56.8 |
| Meningioma | 1,172 | 81.9 | 79.4-84.2 | 75.0 | 72.1-77.7 | 70.1 | 66.9-73.0 | 67.2 | 63.8-70.3 | 64.6 | 61.1-67.9 | 57.4 | 53.2-61.4 |
| Lymphoma | 4,818 | 53.0 | 51.5-54.4 | 44.5 | 43.0-46.0 | 39.3 | 37.8-40.8 | 35.7 | 34.2-37.3 | 33.5 | 31.9-35.0 | 25.9 | 24.1-27.7 |
| TOTAL: All Brain and Other Nervous System i | 77,454 | 59.6 | 59.3-60.0 | 45.2 | 44.8-45.6 | 39.7 | 39.3-40.1 | 36.8 | 36.5-37.2 | 34.9 | 34.6-35.3 | 29.3 | 28.9-29.7 |
aThe cohort analysis of survival rates was utilized for calculating the survival estimates presented in this table. Long-term cohort-based survival estimates reflect the survival experience of individuals diagnosed over the time period, and they may not necessarily reflect the long-term survival outlook of newly diagnosed cases.
bRates are an estimate of the percentage of patients alive at one, two, five, and ten years, respectively. Rates were not presented for categories with 50 or less cases and were suppressed for rates where less than 16 cases were surviving within a category.
cEstimated by CBTRUS using Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) SEER*Stat Database: Incidence -SEER 18 Regs Research Data + Hurricane Katrina Impacted Louisiana Cases, Nov 2016 Sub (2000-2014) <Katrina/Rita Population Adjustment> -Linked To County Attributes - Total U.S., 1969-2015 Counties, National Cancer Institute, DCCPS, Surveillance Research Program, Surveillance Systems Branch, released April 2017, based on the November 2016 submission.
dTotal number of case that occurred within the SEER registries between 2000 and 2014.
eICD-O-3 histology codes: 9470/3, 9471/3, 9472/3, 9474/3.
fICD-O-3 histology code: 9473/3.
gICD-O-3 histology code: 9508/3.
hICD-O-3 histology codes: 8963/3, 9364/3, 9480/3, 9490/0, 9490/3, 9500/3, 9501/3, 9502/3.
iTotal includes histologies not listed in this table.
Abbreviation: SEER, Survival, Epidemiology, and End Results; CI, confidence interval; NOS, not otherwise specified.