Skip to main content
. Author manuscript; available in PMC: 2017 Nov 17.
Published in final edited form as: Eur J Neurosci. 2009 Jul 9;30(2):229–241. doi: 10.1111/j.1460-9568.2009.06813.x

Fig. 3.

Fig. 3

Microinjection of the microglia inhibitor minocycline (25 μg) into the rostroventromedial medulla (RVM) produced a time-dependent attenuation of carrageenan-induced thermal hyperalgesia (A) and tactile allodynia (B). *Significant (P < 0.05) increases in responses relative to the post-carrageenan values. BL, mean baseline responses; Carr., mean post-carrageenan responses. (C) Paw volumes (mL) were measured 30 min after microinjection into the RVM of minocycline or vehicle in rats treated with carrageenan or saline. No significant difference was observed after the microinjection of minocycline into the RVM.