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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Bone. 2017 Aug 15;105:103–114. doi: 10.1016/j.bone.2017.08.006

Figure 3. +/+ and m/m have similar trabecular bone loss in vertebrae with age.

Figure 3

(A) Representative images of L5 vertebrae, and (B) vertebral microarchitecture examined in +/+ and m/m from 16 to 78 wks of age. Trabecular microarchitecture was measured by μCT and bone volume/total volume (BV/TV), trabecular number (Tb.N.), trabecular thickness (Tb.Th), trabecular separation (Tb.Sp.), connectivity density (Conn.D.), and structural modeling index (SMI) were calculated. Closed circles (+/+) and open squares (m/m) represent mean ± SEM of n=8–10 per group. 2-way ANOVA: P <0.0001 for genotype in all measurements except Tb.Th. (not significant). Post hoc: *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001 compared to +/+.