Table 4. Comparison with other published vaccine effectiveness estimates, by season, and other study characteristics.
| Influenza season | Author, Year | Setting | Location | Age group | Adjusted VE (95% CI) | Ontario VE |
|---|---|---|---|---|---|---|
| 2010–11 | Cowling, 2014 [19] | Inpatient | Hong Kong | 6mo-17 years | 84 (44, 96) | 73 (53, 85) |
| Chung, 2016 [18] | Outpatient | USA (Flu VE Network) | 2–8 years | 70 (53, 81) | ||
| Kafatos, 2013 [22] | Outpatient | United Kingdom | <5 years | 72 (12, 91) | ||
| Englund, 2013 [20] | Outpatient | Germany | 0–14 years | 84 (24, 97) | ||
| 2011–12 | Turner, 2014 [33] | Inpatient | New Zealand | 6mo-5 years | 75 (–100, 97) | 54 (19, 73) |
| Cowling, 2014 [19] | Inpatient | Hong Kong | 6mo-17 years | 51 (10, 74) | ||
| Menniti-Ipolito, 2014 [25] | ED/Inpatient | Italy | 6mo-16 years | 41 (–126, 84) | ||
| Chung, 2016 [18] | Outpatient | USA (Flu VE Network) | 2–8 years | 51 (22, 69) | ||
| Skowronski, 2014 [31] | Outpatient | Canada | 1–19 years | 64 (23, 84) | ||
| Pebody, 2013 [27] | Outpatient | United Kingdom | <5 years | 52 (–446, 96) | ||
| Kissling, 2013 [24] | Outpatient | Europe (I-MOVE) | <15 years | 19 (–170, 76) | ||
| Wang, 2016 [35] | Outpatient/ED | China | 6–59 months | 67 (41, 82) | ||
| 2012–13 | Turner, 2014 [32] | Inpatient | New Zealand | 6mo-17 years | 78 (2, 95) | 12 (–31, 40) |
| Cowling, 2014 [19] | Inpatient | Hong Kong | 6mo-17 years | 81 (37, 94) | ||
| Menniti-Ipolito, 2014 [25] | ED/Inpatient | Italy | 6mo-16 years | 26 (–153, 78) | ||
| Chung, 2016 [18] | Outpatient | USA (Flu VE Network) | 2–8 years | 46 (27, 60) | ||
| Kissling, 2014 [23] | Outpatient | Europe (I-MOVE) | 0–14 years | 36 (–41, 71)* | ||
| Fu, 2015 [21] | Outpatient | China | 8mo-6 years | 67 (58, 74)† | ||
| Skowronski [30] | Outpatient | Canada | 1–19 years | 87 (65, 95) | ||
| Ohmit, 2015[26] | Outpatient | USA (HIVE) | <9 years | –4 (–110, 49) | ||
| 2013–14 | Blyth, 2016 [17] | Inpatient | Australia | 6mo-16 years | 56 (12, 78) | 60 (37, 75) |
| Pierse, 2016 [28] | Inpatient | New Zealand | 6mo-17 years | –30 (–212, 46) | ||
| Chung, 2016 [18] | Outpatient | USA (Flu VE Network) | 2–8 years | 61 (34, 77) | ||
| Skowronski, 2015 [29] | Outpatient | Canada | 1–19 years | 77 (47, 90) | ||
| Valenciano, 2015 [34] | Outpatient | Europe (I-MOVE) | 0–14 years | 64 (–86, 93) | ||
| Ohmit, 2016 [5] | Outpatient | USA (HIVE) | <9 years | 68 (10, 88)† |
*Estimate is for H3N2 only;
†Estimate is for H1N1 only.
ED, emergency department