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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2017 Nov 8;44(6):631–640. doi: 10.1007/s10928-017-9554-9

Figure 1.

Figure 1

Pharmacokinetic model used simulate plasma and tissue data for 100 data sets used in the method comparison. Plasma data was simulated from the central compartment, and tissue data from the tissue-1 compartment. Parameters are defined in Table 1.