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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2017 Nov 8;44(6):631–640. doi: 10.1007/s10928-017-9554-9

Figure 2.

Figure 2

Rich plasma and sparse tissue sampling times for the 3×7 and 4×8 designs. Each colored × represents a different participant’s tissue sampling time. For the 3×7, there are 21 participants total, and 32 for the 4×8 design. All participants (represented by the stars) provided 9 plasma samples over the 336 hour sampling.