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A and B, IgE ELISA (Fig 2, A) and mediator release assays (Fig 2, B) using sera of donors with birch pollen allergy with PFS to apple and hazelnut. C, Log(SI) values of TCLs from donors with birch pollen allergy stimulated with 0.5 μg of antigen per well. P values of less than .05 calculated with ANOVA were considered significant. Data of mediator release assays were transformed before analysis (y = log[y]). **P < .01 and ***P < .001. ns, Not significant; SI, stimulation index.
