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. Author manuscript; available in PMC: 2018 Sep 25.
Published in final edited form as: Angew Chem Int Ed Engl. 2017 Sep 1;56(40):12229–12233. doi: 10.1002/anie.201705202

Table 1.

Scope of [3+1] ring expansion.

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Standard conditions: Slow addition of the diazoester (1.3 equiv) to aziridine (1.0 equiv) over 2 h. Numbers refer to isolated yields.

[a]

2.0 equiv of the diazoesters were used.

[b]

4 equiv of the diazoesters were used.

[c]

4.0 equiv of the iodonium ylide were added as two portions over 15 min.

[d]

2.5 equiv of the diazoester were used at 40 °C.