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. 2017 Sep 29;5(4):e261–e271. doi: 10.1016/j.esxm.2017.06.006

Figure 5.

Figure 5

Effect of miR-328a on erectile function in rats. Panel A shows the number of ED(−) and ED(+) rats after transfection (n = 10 per group; *P < .05 vs miR-NC). Panel B shows ICP/MAP ratio (n = 10 per group; *P < .05 vs miR-NC). Panel C shows representative ICP tracing response to stimulation of the cavernous nerve (5 V, 10 Hz, and 60-second duration) in rats (n = 10 per group). Panel D shows miR-328a–attenuated HMOX1 mRNA expression (n = 5 per group). Panel E shows miR-328a–attenuated HO-1 protein expression (n = 5 per group; *P < .05; **P < .01 vs miR-NC). ED(−) = without erectile dysfunction; ED(+) = with erectile dysfunction; GAPDH = glyceraldehyde 3-phosphate dehydrogenase; HO-1 = heme oxygenase-1; ICP = intracorporal pressure; MAP = mean arterial pressure; miR-NC = negative control for miR-328a.