Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of Lyn augments apoptosis in cells expressing GADD34. HEK293 cells were transfected with 5 μg each of constructs indicated. Western blots showed equal levels of FLAG-GADD34 in transfectants (data not shown). Cells were left untreated or treated with MMS as indicated for 12 h. Where indicated,10 μM PP1 was added to cells 10 min before MMS. DNA was extracted and analyzed by electrophoresis through agarose gel. Results are representative of three independent experiments.
