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. 2017 Nov 16;14:223. doi: 10.1186/s12974-017-0994-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — . Repeated low-dose LPS intraperitoneal injection preconditioning did not cause dopaminergic neuronal loss in the SN. We carried out immunohistochemical staining of TH and stereological counting of TH-positive neurons in the non-intracranial injected SN of rats at 1, 7, 14, and 28 days after the peripheral LPS injection. There was no significant differences between the control group and any other time points of the LPS (i.p.) group in the total numbers of TH-positive cells. a Immunohistochemistry staining on frozen sections of TH in the control group and any other time points of the LPS (i.p.) group. b Total numbers of TH-positive neurons in the right SN collected by stereological counting (n = 3, each group). The data are presented as the mean ± SEM. Scale bars, 250 μm (40×), 100 μm (100×), and 25 μm (200×)