Table 4.

Promising formulations for the treatment of bacterial infections

Lipid(s) and sterol used	Bacteria or disease	Cell line/animal model used	Administration route	Promising liposome formulation	References
PC/PG/Chol, PC/PG/Chol/Man-PE, PC/PS/Chol, PC/DMTAP/Chol	Meningitis	Monocyte-derived human DCs and murine bone marrow-derived DCs	N/A	PC/PG/Chol/Man-PE and PC/DMTAP/Chol	[94]
PC/Chol/SA, PC/Chol/PA and PC/Chol	Diphteria toxin	BALB/c, C57BL/6 and ddY mice; P815, P13.1 and CD8OVA cells	Subcutaneous	PC/Chol/SA	[93]
DOTAP and DOPC	Melioidosis	Neutrophils and splenocytes from BALB/c mice	Intramuscular	DOTAP	[2]
DOPE/DOTAP	E. coli	Mouse embryonic fibroblasts (MEF) and RAW 264.7 macrophages	N/A	DOPE/DOTAP	[92]
DDA/Chol/Man-C6-Chol and DDA/Chol	E. coli	DC 2.4 cells	N/A	DDA/Chol/Man-C6-Chol	[19]

Cell cultures and no vaccination in animal models were employed

N/A not applicable