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. 2017 Nov 16;17:769. doi: 10.1186/s12885-017-3769-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Differences in microvessel density between tumors with and without venous invasion. The microvessel density (MVD) in tumors with venous invasion was significantly higher compared with that in tumors without venous invasion. MVD was a significant risk factor for venous invasion in hindgut neuroendocrine tumors (Mann–Whitney U test, P < 0.001; values are expressed as the mean ± standard deviation)