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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Cell Biochem Biophys. 2017 Jun 29;75(3-4):335–349. doi: 10.1007/s12013-017-0813-6

Figure 5.

Figure 5

Hydropropidine as a cell membrane-impermeable probe for superoxide. (A) Chemical structures of HPr+ and the superoxide-specific oxidation product, 2-OH-Pr2+. (B) Comparison of the cell-medium distribution of HE and HPr+ probes upon incubation with RAW 264.7 cells. (Reprinted from Free Radic. Biol. Med., vol. 54, Michalski, R., Zielonka, J., Hardy, M., Joseph, J., & Kalyanaraman, B., Hydropropidine: a novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide, 135–147. Copyright 2013, with permission from Elsevier.) (72)