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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Pharm Res. 2017 Jul 5;34(10):2131–2141. doi: 10.1007/s11095-017-2219-y

Table 3.

Estimated model parameters for CL (mL/min) vs. size relationship obtained following simultaneous fitting approach, along with CV% for each parameter

Parameter Estimate %CV
V1 (mL) 1.15 >50
α (mL) 3.44 >50
κ 2.33E-02 0.909
γ (mL/min) 37.50 >50
μ 2.48 0.297
β (mL/min) 24.98 >50
λ 1.97 6.37E-02
B (mL/min) 3.90 NA
L 5.10 NA