Table 3.

Percentage of epithelial cells (table values) within G13 receiving 50, 90 and 99% of total absorbed dose for each case.

	Budesonide (BD)			Fluticasone propionate (FP)
	50% of dose	90% of dose	99% of dose	50% of dose	90% of dose	99% of dose
2.64 μm Microparticles
No motion (% cells)	0.013	0.022	0.022	0.013	0.03	0.03
Slow clearance (% cells)	0.084	0.43	0.62	0.063	0.26	0.51
Fast clearance (% cells)	0.32	1.3	1.7a	0.77	2.3	3.0
2.64 μm Nanoaggregates
Slow clearance (% cells)	0.40	1.5	2.2	4.4	24.3	41.3
Fast clearance (% cells)	0.44	1.7	2.4	5.0	25.9	43.0
50 nm Nanoaerosol
Fast clearance (% cells)	19.9	53.4	63.1	19.1	67.8	92.3b

In uniform absorption 50% of the dose should be received by 50% of the cells (linear relation).

^aHighly nonuniform absorption with 99% of the absorbed dose received by only 1.7% of the cells.

^bUniform absorption with 99% of absorbed dose received by 92.3% of the cells.