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. 2017 Nov 16;143(11):954–955. doi: 10.1001/jamaoto.2017.0977

Figure 2. Inhibition of Collagen Types I and III Gene Expression in Laryngotracheal Stenosis (LTS)–Derived Fibroblasts.

Figure 2.

Gene expression is presented as the relative fold change calculated as the cycle threshold (CT) normalized against β-actin and compared with the expression in normal airway fibroblasts (2−ΔΔCT). Interferon-γ reduced gene expression 5.51-fold in COL1 (95% CI, 3.31-9.15) and 3.07-fold in COL3 (95% CI, 1.99-4.72) in LTS-derived fibroblasts compared with untreated fibroblasts in all 6 patient samples. Gene expression was normalized to normal airway fibroblasts. Error bars indicate 95% CIs. INF-γ indicates interferon-γ.

aP = .03.