Table 1.
Study Population Characteristics At Cohort Entry
| Hispanic Patients |
Non-Hispanic White Patients |
Difference (95% CI) |
p-Value | |
|---|---|---|---|---|
| Number (%) | 1,493 (9.9) | 13,525 (90.1) | ||
| Age, yeara | 6.9 (6.5–7.4) | 6.8 (6.5–7.1) | 0.1 (0 to 0.3) | <0.001 |
| Sex, male | 826 (53.1) | 7,233 (51.1) | 2.0 (−1.7 to 5.6) | 0.1 |
| PERT | 1,343 (88.5) | 12,755 (92.3) | 3.8 (2.1 to 5.7) | <0.001 |
| Sweat Chloride Concentrationa | 94.7 (93.5–95.9) | 97.1 (96.7–97.5) | −2.4 (−3.5 to −1.2) | <0.001 |
| Age At Diagnosis, mthsa | 6.3 (1.6–38.4) | 4.5 (0.7–25.7) | 1.8 (0.9 to 12.7) | <0.001 |
| Body Mass Indexa | ||||
| Percentile (if <20yo) | 54.1 (53.6–55.6) | 50.6 (50.1–51.0) | 3.6 (2.0 to 5.1) | <0.001 |
| BMI kg/m2 (if ≥20yo) | 24.0 (21.0–27.0) | 23.3 (22.1–24.5) | 0.7 (−2.6 to 3.9) | 0.7 |
| Pseudomonas aeruginosa | 597 (38.3%) | 4,766 (33.6%) | 4.7 (0.6 to 9.0) | <0.001 |
| MRSA | 195 (12.5%) | 2,272 (16.0%) | −3.5 (−4.5 to −2.3) | 0.001 |
| CF Related Diabetes | 63 (4.1%) | 688 (4.9%) | −0.8 (−7.6 to 4.7) | <0.001 |
| Tobacco Exposure | <0.001 | |||
| None | 776 (49.8%) | 6,476 (45.7%) | 4.1 (0.3 to 7.9) | |
| Secondhand | 100 (6.4%) | 1,288 (9.1%) | −2.7 (−7.0 to 4.2) | |
| Active Smoker | 8 (0.5%) | 84 (0.6%) | −0.1 (−5.0 to 37.1) | |
| Maternal Education | <0.001 | |||
| College & Higher | 231 (15.5%) | 3,625 (26.8%) | −11.3 (−12.3 to −10.0) | |
| No College | 316 (20.3%) | 2,051 (14.5%) | 5.8 (1.2 to 10.9) | |
| Insurance | <0.001 | |||
| No Medicaid | 539 (34.6%) | 7.718 (54.5%) | −19.9 (−24.1 to −15.6) | |
| Medicaid | 901 (57.9%) | 5,878 (41.5%) | 16.4 (12.9 to 19.9) | |
| No Insurance | 31 (2.0%) | 88 (0.6%) | 1.4 (−3.7 to 14.2) | |
| F508del | <0.001 | |||
| Two copies | 403 (25.9%) | 7,070 (49.9%) | −24.0 (−28.4 to −19.3) | |
| One copy | 583 (37.4%) | 5,100 (36.0%) | 1.4 (−2.8 to 5.7) | |
| No copies | 469 (30.1%) | 1,472 (10.4%) | 19.7 (15.3 to 24.3) | |
| CFTR Mutation Class | <0.001 | |||
| Class I–III | 800 (51.4%) | 10,503 (74.1%) | −22.7 (−26.3 to −19.1) | |
| Class IV–V | 133 (8.5%) | 1,033 (7.3%) | 1.2 (−3.3 to 7.5) | |
| Not Classified | 522 (33.5%) | 2,106 (14.9%) | 18.6 (14.3 to 23.1) | |
| Location In U.S. | <0.001 | |||
| West | 545 (35.0%) | 2,266 (16.0%) | 19 (14.7 to 23.4) | |
| Midwest | 451 (29.0%) | 5,070 (35.8%) | −6.8 (−11.2 to −2.2) | |
| Northeast | 236 (15.2%) | 3,181 (22.5%) | −7.3 (−11.9 to −1.9) | |
| South | 282 (18.1%) | 3,511 (24.8%) | −6.3 (−11.2 to −1.5) |
a)
Median (Interquartile range)
-All other values are reported as percentages